Post by Ava on Oct 26, 2018 17:23:50 GMT
Is Nitric Oxide a Cancer-Healing Powerhouse?
Nitric Oxide (NO) is one of the most studied substances out there and is considered a “substance of interest” for slowing and even stopping tumor growth. Like many powerful yet still mysterious processes in the body, some studies show conflicting results on how Nitric Oxide affects cancer cells. However, recent research is getting closer to discovering the specific conditions which can trigger NO-related and NO-inspired tumor suppression − making it potentially one of the strongest yet little-known cancer-fighters.
Nitric Oxide is a Powerful Genetic Regulator
Nitric Oxide was discovered in 1998 by three American physicians who eventually went on to win the Nobel Prize for their research. Since then, the overall importance of Nitric Oxide for the body has become common knowledge. NO is a ubiquitous, water soluble, free radical gas produced by the body’s own cells.
Its main job is to transmit signals to other cells in the body. It is first and foremost a “pleiotropic regulator,” i.e. it helps determine how genes express themselves in a multitude of ways. Nitric Oxide is critical to many key biological processes, including neurotransmission, immune system function, and vascular health.
It is also a promoter of cell growth, which can make it both a cancer tumor promoter under certain circumstances, as well as a cancer suppressor. One of the most powerful ways it can help heal cancer is by encouraging the growth of healthy cells.
According to a review published in a 2013 edition of the Journal of Surgical Oncology, “NO has been suggested to modulate different cancer-related events including angiogenesis, apoptosis, cell cycle, invasion, and metastasis. On the other hand, it is also emerging as a potential anti-oncogenic agent.”
A London-based study may have found clues as to what makes it either anti-cancer or pro-proliferation:
“It appears that high levels of NOS expression (for example, generated by activated macrophages) may be cytostatic or cytotoxic for tumor cells, whereas low level activity can have the opposite effect and promote tumor growth. Paradoxically therefore, NO (and related reactive nitrogen species) may have both genotoxic and angiogenic properties.”
Can Upping Your Nitric Oxide Levels Help You Heal Cancer?
Although the jury is still out as to the exact “low point” at which NO may increase cancer tumor growth, what is crystal clear (and verified by countless studies) is that Nitric Oxide at a high level is a tumor suppressor. Being proactive with prevention by upping your NO levels naturally may help prevent and even heal cancer.
The most promising research regarding NO levels and cancer has been around the amino acid L-Arginine. L-Arginine works with nitric oxide synthase (NOS) to produce nitric oxide. A study conducted in 2000 and published in the journal Tumour Biology tested several Breast Cancer cell lines. They found that in the lines with the highest NO activity, the nitric oxide present caused breast cancer cells to implode.
Another study published in Rockefeller University’s Journal of Experimental Medicine found that tumor cells were destroyed by “active macrophages” (cells found in the immune system’s white blood cells) when NO activity in tumor cells in mice was stimulated. On the other hand, when NO activity was lowered significantly, the tumor cells developed the capacity to avoid immune system-related destruction.
Read more:
thetruthaboutcancer.com/nitric-oxide/?utm_campaign=mail-cancer-chocolate&utm_medium=email&utm_source=email&utm_content=cancer-fighting-chocolate&mpweb=144-7389694-743203021
Nitric Oxide (NO) is one of the most studied substances out there and is considered a “substance of interest” for slowing and even stopping tumor growth. Like many powerful yet still mysterious processes in the body, some studies show conflicting results on how Nitric Oxide affects cancer cells. However, recent research is getting closer to discovering the specific conditions which can trigger NO-related and NO-inspired tumor suppression − making it potentially one of the strongest yet little-known cancer-fighters.
Nitric Oxide is a Powerful Genetic Regulator
Nitric Oxide was discovered in 1998 by three American physicians who eventually went on to win the Nobel Prize for their research. Since then, the overall importance of Nitric Oxide for the body has become common knowledge. NO is a ubiquitous, water soluble, free radical gas produced by the body’s own cells.
Its main job is to transmit signals to other cells in the body. It is first and foremost a “pleiotropic regulator,” i.e. it helps determine how genes express themselves in a multitude of ways. Nitric Oxide is critical to many key biological processes, including neurotransmission, immune system function, and vascular health.
It is also a promoter of cell growth, which can make it both a cancer tumor promoter under certain circumstances, as well as a cancer suppressor. One of the most powerful ways it can help heal cancer is by encouraging the growth of healthy cells.
According to a review published in a 2013 edition of the Journal of Surgical Oncology, “NO has been suggested to modulate different cancer-related events including angiogenesis, apoptosis, cell cycle, invasion, and metastasis. On the other hand, it is also emerging as a potential anti-oncogenic agent.”
A London-based study may have found clues as to what makes it either anti-cancer or pro-proliferation:
“It appears that high levels of NOS expression (for example, generated by activated macrophages) may be cytostatic or cytotoxic for tumor cells, whereas low level activity can have the opposite effect and promote tumor growth. Paradoxically therefore, NO (and related reactive nitrogen species) may have both genotoxic and angiogenic properties.”
Can Upping Your Nitric Oxide Levels Help You Heal Cancer?
Although the jury is still out as to the exact “low point” at which NO may increase cancer tumor growth, what is crystal clear (and verified by countless studies) is that Nitric Oxide at a high level is a tumor suppressor. Being proactive with prevention by upping your NO levels naturally may help prevent and even heal cancer.
The most promising research regarding NO levels and cancer has been around the amino acid L-Arginine. L-Arginine works with nitric oxide synthase (NOS) to produce nitric oxide. A study conducted in 2000 and published in the journal Tumour Biology tested several Breast Cancer cell lines. They found that in the lines with the highest NO activity, the nitric oxide present caused breast cancer cells to implode.
Another study published in Rockefeller University’s Journal of Experimental Medicine found that tumor cells were destroyed by “active macrophages” (cells found in the immune system’s white blood cells) when NO activity in tumor cells in mice was stimulated. On the other hand, when NO activity was lowered significantly, the tumor cells developed the capacity to avoid immune system-related destruction.
Read more:
thetruthaboutcancer.com/nitric-oxide/?utm_campaign=mail-cancer-chocolate&utm_medium=email&utm_source=email&utm_content=cancer-fighting-chocolate&mpweb=144-7389694-743203021